COVID-19 and serum vitmamine d levels: an integrative review of clinical prognostic correlation in infected patients

Abstract

Objective: To identify evidence in the medical literature regarding the correlation between serum vitamin D levels and the prognosis of patients infected with Sars-CoV-2 (COVID-19). Method: This study is an integrative review based on the databases: PubMed, MedLine Plus and Google Scholar. Results: A total of 7 articles were analyzed, which presented the necessary results for this review and conclusions about the influence of body levels of Vitamin D and the clinical outcome of patients affected by the new Coronavirus. Conclusion: The researches analyzed describe the prevalence of the association between Vitamin D deficiency and worse symptom evolution in patients affected by COVID-19 in the majority. Satisfactory (not deficient) levels of vitamin D in affected patients are associated with shorter hospital stay and less need for oxygen therapy. However, the use of vitamin D as a treatment still requires confirmation with clinical trials.