Farmacologia clínica e a falta de efetividade não quantitativa de fármacos para diabetes mellitus II: avaliação de critérios relativos à química farmacêutica e aos hábitos de uso de medicamentos

Luciano  Henrique Pinto; Micael  Batista Pereira Santos; Thais Laini Simões; Marian  Felisberto Bitencourt; Hauana  Heilig Martins; Luciana  Ferreria Karstens

doi:10.36489/saudecoletiva.2021v11i68p7771-7782

Authors

Luciano Henrique Pinto Professor adjunto de farmacologia e química farmacêutica. Departamentos de Medicina, Enfermagem e Farmácia, Universidade da Região de Joinville, UNIVILLE, Coordenador do Projeto Integrado ECOSAM. https://orcid.org/0000-0003-0250-7502
Micael Batista Pereira Santos Graduandos em Farmácia, Universidade da Região de Joinville, UNIVILLE. https://orcid.org/0000-0003-3347-8847
Thais Laini Simões Graduandos em Farmácia, Universidade da Região de Joinville, UNIVILLE. https://orcid.org/0000-0002-9547-9522
Marian Felisberto Bitencourt Graduanda em Medicina, Universidade da Região de Joinville, UNIVILLE. https://orcid.org/0000-0003-1467-3356
Hauana Heilig Martins Graduandas em Medicina, Universidade da Região de Joinville, UNIVILLE. https://orcid.org/0000-0003-1003-037X
Luciana Ferreria Karstens Professora Adjunto, Departamentos de Enfermagem, Universidade da Região de Joinville, UNIVILLE, Colaboradora do Projeto Integrado ECOSAM. https://orcid.org/0000-0001-9843-3047

DOI:

https://doi.org/10.36489/saudecoletiva.2021v11i68p7771-7782

Keywords:

Diabetes Mellitus, Evaluation of the Efficacy-Effectiveness of Interventions, Drug Therapy, Unified Health System

Abstract

Objective: to problematize and alert to non-quantitative issues involving non-therapeutic success in patients with Diabetes Mellitus II (DM II). Method: the study carried out in two Basic Family Health Unit Centers, in Joinville city, Santa Catarina State, Brazil. The studied population corresponded to users of chronic DM II drugs; under drug treatment and registered in medical records. Data collection took place through interviews and analysis of medical records. Results: A total of 222 patients, between 42 and 82 years old, were selected in the study. The analysis of the presence of factors that lead to lack of non-quantitative effectiveness (FLNQE) resulted in an average of 3.09 causes of non-effectiveness per patient. Conclusion: FLNQE are present, especially in newly diagnosed and polypharmacy patients, also with age as a contributing factor. New studies have helped to better understand this phenomenon.