Toxicidades agudas do tratamento com quimiorradioterapia em pacientes com câncer de cabeça-pescoço

Anne Kettley  Lacerda de Lima Gonzaga; Maria Júlia Oliveira Ramos; Simone Yuriko Kameo; Bruna Eloise Lenhani; Jéssica dos Santos Costa; Glebson Moura Silva; Andrea Velasco dos Santos Silva; Edenice de Oliveira Santana

doi:10.36489/saudecoletiva.2022v12i79p11171-11184

Authors

Anne Kettley Lacerda de Lima Gonzaga https://orcid.org/0000-0002-3705-4825
Maria Júlia Oliveira Ramos https://orcid.org/0000-0003-4729-4416
Simone Yuriko Kameo https://orcid.org/0000-0002-0035-2415
Bruna Eloise Lenhani https://orcid.org/0000-0002-6009-3400
Jéssica dos Santos Costa https://orcid.org/0000-0003-2404-6604
Glebson Moura Silva https://orcid.org/0000-0002-4977-2787
Andrea Velasco dos Santos Silva https://orcid.org/0000-0002-3731-9555
Edenice de Oliveira Santana https://orcid.org/0000-0001-8453-455X

DOI:

https://doi.org/10.36489/saudecoletiva.2022v12i79p11171-11184

Keywords:

Head and Neck Neoplasms, Chemoradiotherapy, Toxicity Tests, Acute, Nursing Assessment

Abstract

Objective: To identify and classify as acute toxicities of the concomitant treatment of chemotherapy and radiotherapy in patients with head and neck cancer. Method: Cross-sectional, quantitative, descriptive study. A total of 56 patients with head and neck cancer undergoing chemoradiation therapy in southern Brazil between May and July 2013 were evaluated. Results: The sample showed that 89.3% were men, aged between 46 and 60 years (57.1%). Regarding radiotherapy toxicities, the most affected structures were pharynx and esophagus (94.6%), skin (91.1%) and oral mucosa (76.8%), with a predominance of grades 3, 1 and 2, respectively. About chemotherapy, grade 1 oral mucositis (50%), grade 1 motor peripheral nervous system alteration (46.4%), grade 1 venous network alteration (37.5%) were the main findings. Conclusion: These symptoms compromise treatment adherence and quality of life, requiring regular monitoring and evaluation of patients, in order to avoid serious side effects.

Author Biographies

Anne Kettley Lacerda de Lima Gonzaga

Oncology nurse. Master and Doctoral Student in Sciences at the Ribeirão Preto School of Nursing- University of São Paulo (EERP-USP).

Maria Júlia Oliveira Ramos

Nursing Student at the Federal University of Sergipe-UFS.

Simone Yuriko Kameo

Enfermeira oncológica. Mestre e Doutora em Enfermagem Geral e Especializada. Docente no Departamento de Educação em Saúde de Lagarto (DESL), Universidade Federal de Sergipe-UFS.

Bruna Eloise Lenhani

Oncology nurse. Master and PhD in Nursing from the Federal University of Paraná-UFPR. Adjunct Professor of the Nursing Course at the Santa Cruz University Center in Curitiba – UniSantaCruz.

Jéssica dos Santos Costa

Nurse. Resident in Family Health at the Federal University of Sergipe-UFS.

Glebson Moura Silva

Nurse. PhD in Education at the Federal University of Sergipe-UFS. Professor, Department of Nursing, UFS – Campus Lagarto, Sergipe, Brazil.

Andrea Velasco dos Santos Silva

Oncology nurse. Preceptor of the Multiprofessional Residency in Cancerology (nursing area), Hospital Erasto Gaertner, Curitiba, Paraná, Brazil.

Edenice de Oliveira Santana

Nurse. Master in Nursing from the Federal University of Paraná-UFPR. Coordinator of the Multiprofessional Residency in Cancerology, Nursing Area, Hospital Erasto Gaertner, Curitiba, Paraná, Brazil.

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