Influence of genetic and environmental factors on the manifestation of atopic dermatitis in twins: A case report
DOI:
https://doi.org/10.36489/saudecoletiva.2022v12i80p11360-11367Keywords:
Atopic Dermatitis, Twins, genetics, Environmental ExposureAbstract
Objective: to highlight the influence of the interaction of genetic and environmental factors in the manifestation of atopic dermatitis, through the observation of different outcomes in twins. Method: The information contained in this clinical case description was obtained through anamnesis, physical examination, complementary exams and review of the literature referenced in this work. Results: We report the case of 21-year-old twins with a history of very similar exposure to external antigens and who were diagnosed with AD in childhood, with different evolutions in adolescence and adulthood. Conclusion: twins are assumed to share environmental risk factors and, therefore, by comparing them, it is possible to estimate the relative impact of genetic and environmental factors on a given disease.
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