Use of chlorhexidine for oral hygiene in the ICU: Systematic review and meta-analysis
DOI:
https://doi.org/10.36489/saudecoletiva.2023v13i84p12395-12407Keywords:
Chlorhexidine, Oral hygiene in ICU, Pneumonia Associated with mechanical ventilation, Pneumonia, Intensive care unitAbstract
Objectives: to identify the different ways of using chlorhexidine for oral hygiene of patients in an ICU environment and which one provides the highest rate of VAP reduction. Methods: a Systematic Review was carried out, which had as a PICO strategy, patients admitted to the ICU, subjected to oral hygiene with chlorhexidine, evaluating the result on the reduction of VAP. Results: 0.12% chlorhexidine solution is the most used and generated a meta-analysis with 5 studies that showed that there is no statistical significance in the use of chlorhexidine in oral hygiene in these patients [RR 0.69 (95% CI % = 0.46 - 1.03)]. Conclusion: despite the growing use of oral hygiene with chlorhexidine in the ICU, there is no scientific evidence that it provides greater benefit in reducing VAP and, therefore, a better evaluation of the benefit in its frequent use is recommended.
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