Vaccination situation and severity of hospitalization due to severe acute respiratory syndrome due to COVID 19, Maranhão, 2021
DOI:
https://doi.org/10.36489/saudecoletiva.2023v13i84p12460-12467Keywords:
COVID-19, Hospitalization, COVID-19 Vaccines, VaccinesAbstract
Objective: to characterize and compare hospitalizations due to COVID-19 in Maranhão, according to the vaccination status against the disease. Method: This is a retrospective cohort study, based on secondary data. Results: In 2021, 13,257 individuals hospitalized with COVID-19 were registered, of which 6,425 (48.46%) evolved to discharge after non-serious hospitalization, 1,573 (11.87%) evolved to discharge with severe hospitalization and 5,259 (39 .67%) evolved to death. In all three outcomes of the evolution of hospitalizations, the number of unvaccinated individuals is much higher when compared to those vaccinated. Conclusion: Our results reinforce the important role of vaccination in reducing the severity of hospitalizations due to COVID-19. With the immunization of the state population, few hospitalized individuals who were immunized evolved to severe discharge and death.
References
Ranzani, O. T., Bastos, L. S. L., Gelli, J. G. M., Marchesi, J. F., Baião, F., Hamacher, S., & Bozza, F. A. Characterisation of the first 250,000 hospital admissions for COVID-19 in Brazil: a retrospective analysis of nationwide data. The Lancet. Respiratory medicine, 9(4), 407–418, 2021.https://doi.org/10.1016/S2213-2600(20)30560-9
PAINEL CONASS | COVID-19 [Internet]. www.conass.org.br. Available from: https://www.conass.org.br/painelconasscovid19/
BRASIL. Ministério da Saúde. Secretaria de Vigilância em Saúde. Secretaria Extraordinária de Enfrentamento à COVID-19. Plano Nacional de Operacionalização da Vacinação Contra a COVID-19.2022.
Passarelli-Araujo, H., Pott-Junior, H., Susuki, A. M., Olak, A. S., Pescim, R. R., Tomimatsu, M. F. A. I., Volce, C. J., Neves, M. A. Z., Silva, F. F., Narciso, S. G., Aschner, M., Paoliello, M. M. B., & Urbano, M. R. The impact of COVID-19 vaccination on case fatality rates in a city in Southern Brazil. American journal of infection control, 50(5), 491–496, 2022. https://doi.org/10.1016/j.ajic.2022.02.015.
Vasileiou, E.; Simpson, C.R.; Shi, T.; Kerr, S.; Agrawal, U.; Akbari, A.; Bedston, S.; Beggs, J.; Bradley, D.; Chuter, A.; et al. Interim findings from first-dose mass COVID-19 vaccination roll-out and COVID-19 hospital admissions in Scotland: A national prospective cohort study. Lancet 2021, 397, 1646–1657. DOI:10.2139/ssrn.3789264.
Hitchings, M. D. T., Ranzani, O. T., Torres, M. S. S., de Oliveira, S. B., Almiron, M., Said, R., Borg, R., Schulz, W. L., de Oliveira, R. D., da Silva, P. V., de Castro, D. B., Sampaio, V. S., de Albuquerque, B. C., Ramos, T. C. A., Fraxe, S. H. H., da Costa, C. F., Naveca, F. G., Siqueira, A. M., de Araújo, W. N., Andrews, J. R., … Croda, J. Effectiveness of CoronaVac among healthcare workers in the setting of high SARS-CoV-2 Gamma variant transmission in Manaus, Brazil: A test-negative case-control study. Lancet regional health. Americas, 1, 100025, 2021. https://doi.org/10.1016/j.lana.2021.100025
Oliveira LN de, Santos AKF de S, Carvalho RMC de, Cosme FH de S, Querino CAC, Nascimento RF do, Macedo CL. Avaliação da eficácia e segurança das principais vacinas utilizadas contra COVID-19 no Brasil / Evaluation of the efficacy and safety of the main vaccines used against COVID-19 in Brazil. Braz. J. Develop. [Internet]. 2022 Apr. 28 [cited 2023 Jan. 4];8(4):31753-67. Available from: https://ojs.brazilianjournals.com.br/ojs/index.php/BRJD/article/view/47202
Victora, P. C., Castro, P. M. C., Gurzenda, S., Medeiros, A. C., França, G. V. A., & Barros, P. A. J. D. Estimating the early impact of vaccination against COVID-19 on deaths among elderly people in Brazil: Analyses of routinely-collected data on vaccine coverage and mortality. EClinicalMedicine, 38, 101036, 2021. https://doi.org/10.1016/j.eclinm.2021.101036
Alencar, C. H., Cavalcanti, L. P. G., Almeida, M. M., Barbosa, P. P. L., Cavalcante, K. K. S., Melo, D. N., de Brito Alves, B. C. F., & Heukelbach, J. (2021). High Effectiveness of SARS-CoV-2 Vaccines in Reducing COVID-19-Related Deaths in over 75-Year-Olds, Ceará State, Brazil. Tropical medicine and infectious disease, 6(3), 129. https://doi.org/10.3390/tropicalmed6030129
Orellana, J. D.Y., Cunha, G.M, Marrero, L., Leite, I.C, Domingues,C.M.A.S., Horta, B.L.. Mudanças no padrão de internações e óbitos por COVID-19 após substancial vacinação de idosos em Manaus, Amazonas, Brasil. Cadernos de Saúde Pública [online]. 2022, v. 38, n. 5 [Acessado 4 Janeiro 2023], PT192321. Disponível em: <https://doi.org/10.1590/0102-311XPT192321>. Epub 16 Maio 2022. ISSN 1678-4464. https://doi.org/10.1590/0102-311XPT192321.
Rosenberg, E. S., Dorabawila, V., Easton, D., Bauer, U. E., Kumar, J., Hoen, R., Hoefer, D., Wu, M., Lutterloh, E., Conroy, M. B., Greene, D., & Zucker, H. A. (2022). Covid-19 Vaccine Effectiveness in New York State. The New England journal of medicine, 386(2), 116–127. https://doi.org/10.1056/NEJMoa2116063
Frias DFR, Romera GR de R, Maziero L de MA, Tebet DGM, Barbosa KF. Efeitos da vacinação contra COVID-19 com relação a evolução dos casos no estado de Mato Grosso do Sul. Rev. Cereus, 13(4):149-57, 2021. Disponível em: http://ojs.unirg.edu.br/index.php/1/article/view/3583
Kerr L, Kendall C, Silva AAM da, Aquino EML, Pescarini JM, Almeida RLF de, et al. COVID-19 no Nordeste brasileiro: sucessos e limitações nas respostas dos governos dos estados. Ciência & Saúde Coletiva. 2020. Disponível em:: https://scielosp.org/pdf/csc/2020.v25suppl2/4099-4120/pt
INSTITUTO BRASILEIRO DE GEOGRAFIA E ESTATÍSTICA-IBGE. Censo Demográfico. Maranhão, 2022
Kerr L, Kendall C, Silva AAM da, Aquino EML, Pescarini JM, Almeida RLF de, et al. COVID-19 no Nordeste brasileiro: sucessos e limitações nas respostas dos governos dos estados. Cien Saude Colet, 2020. Disponível em: https://www.scielo.br/j/csc/a/kYBX8WJpfFGSzmnWDtV5CcT/
Wiersinga WJ, Rhodes A, Cheng AC, Peacock SJ, Prescott HC. Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review. JAMA. 2020;324(8):782–793. doi:10.1001/jama.2020.12839
Miranda, J. DE O. F., & Morais, A. C. A COVID-19 na vida de crianças e adolescentes brasileiros: poucos sintomas e muitos impactos. Revista Enfermagem Contemporânea, 10(1), 6–7. https://doi.org/10.17267/2317-3378rec.v10i1.3708
Rossman H, Shilo S, Meir T, Gorfine M, Shalit U, Segal E. COVID-19 dynamics after a national immunization program in Israel. Nat Med. 2021;27(6):1055-1061. doi:10.1038/s41591-021-01337-2 Wise, J. Covid-19: infections in England fall by two thirds since January. BMJ, v. 18, n. 372, p. 491, 2021.
D'Adamo H, Yoshikawa T, OuslandeR JG. Coronavirus Disease 2019 in Geriatrics and Long-term Care: the ABCDs of COVID-19. J Am Geriatr Soc. 2020;68(5):1-6. https://doi.org/10.1111/jgs.16445
Tavares DMDS, Oliveira NGN, Diniz-Rezende MA, Bitencourt GR, Silva MBD, Bolina AF. Scientific knowledge about infections by the new coronavirus in older adults: a scoping review. Rev Bras Enferm. 2021;74Suppl 1(Suppl 1):e20200938. Published 2021 Apr 14. doi:10.1590/0034-7167-2020-0938
Michelon, C.M. Principais variantes do SARS-CoV-2 notificadas no Brasil. RBAC. 2021;53(2):109-116. https://doi.org/10.21877/2448-3877.202100961
MARANHÃO.Secretaria Estadual de Saúde. Boletim Epidemiológico 02/2022: Monitoramento da circulação das variantes de COVID 19 no Maranhão. 2022. Disponível em: https://www.saude.ma.gov.br/wp-content/uploads/2022/02/BOLETIM-02-MONITORAMENTO-CIRCULACAO-NOVAS-VARIANTES-MA.pdf
