Perfil de segurança de vacinas acelulares contra a coqueluche: uma análise estatística e epidemiológica

Ana Luísa Coraççari Pereira; Isabela Martins da Silva; Sophia Mouta Marin; Maria Eduarda Salles Trevizani; Luana Paula Gomes de Lima; Anderson Sena Barnabe

doi:10.36489/saudecoletiva.2025v16i98p16608-16615

Authors

Ana Luísa Coraççari Pereira Farmacêutica. Faculdades Oswaldo Cruz - São Paulo/SP. https://orcid.org/0009-0004-3683-9649
Isabela Martins da Silva Farmacêutica. Faculdades Oswaldo Cruz – São Paulo/SP. https://orcid.org/0009-0008-1307-8452
Sophia Mouta Marin Farmacêutica. Faculdades Oswaldo Cruz - São Paulo/SP. https://orcid.org/0009-0003-5816-6548
Maria Eduarda Salles Trevizani Farmacêutica. Faculdades Oswaldo Cruz - São Paulo/SP. https://orcid.org/0009-0006-1951-0942
Luana Paula Gomes de Lima Bióloga. Mestre em Biossistemas. Professora do Depto de Saúde das Faculdades Oswaldo Cruz. https://orcid.org/0009-0007-7505-5283
Anderson Sena Barnabe Biólogo. Doutor em Epidemiologia. Professor do Depto de Saúde das Faculdades Oswaldo Cruz; Universidade Cruzeiro do Sul e Instituto de Pesquisa e Educação em Saúde de São Paulo (IPESSP). https://orcid.org/0000-0002-7463-6971

DOI:

https://doi.org/10.36489/saudecoletiva.2025v16i98p16608-16615

Keywords:

Whooping cough, Vaccination, Adverse reactions

Abstract

Objective: An analysis was conducted on observational studies that measured the rates of adverse events of cellular and acellular vaccines against this disease. Method: The search was performed in databases such as PubMed, Scopus, Cochrane, Embase and LILACS, using controlled descriptors and keywords related to pertussis and adverse events to the vaccine. Results: Acellular vaccines had lower incidence rates. Conclusion: It was seen that the safety of this vaccine model is a good predictor of the use of these immunobiologicals.

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